For Rapid antibody tests and ELISA tests the interpretation is the same.
The ELISA test is considered more reliable and also gives a quantitative figure of the amount of antibody (as opposed to a simple positive/negative result with the Rapid test).
There are 4 possible results:
- IgM negative, IgG negative.
- There is no evidence of current infection or previous infection.
- Remember that it takes a minimum of 4 days from the start of symptoms, or 7 days from exposure to the virus before the antibodies show up positive. This means that the antibody test cannot detect an infection in the initial stages.
- If there is a suspicion of recent infection in spite of this result a PCR or Antigen test can be done, or repeat the antibody test after a few days.
- IgM positive, IgG negative:
- This suggests infection in the early stages of the disease.
- The patient is infectious
- If the result does not coincide with the clinical picture (for example, if there are no symptoms) it could be a false positive. The result can be confirmed with a PCR test or, if the test was a Rapid antibody test, by doing an ELISA test, which is more reliable and uses a different method.
- IgM positive, IgG positive:
- This suggests infection in the intermediate stage of the disease.
- The patient is considered no longer infectious.
- IgM negative, IgG positive
- There is recovery from the disease and the patient is not infectious
- There may be some immunity to Covid-19, although it is not known yet to what extent and how long that immunity may last. Precautions should still be taken.
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